Half of women at risk of dementia, Parkinson’s or stroke

PARIS — Nearly half of women and one in three men are at risk of developing stroke or degenerative neurological diseases such as dementia and Parkinson’s during their lifetime, according to a study published on Monday.

Dutch researchers considered all three conditions “in order to grasp how big the problem of incurable brain diseases in late life really is”, said the study’s senior author Arfan Ikram.

“We grouped these diseases together not only because they are common but also because there are indications that these often co-occur and might share some overlapping causes,” Ikram, of the Erasmus MC University Medical Centre Rotterdam in the Netherlands, told AFP.

This could mean there are also overlapping ways to delay or avoid getting the diseases, and the research found that some preventative strategies may cut the risk by between 20 and 50 per cent.

For the study, published in the Journal of Neurology Neurosurgery and Psychiatry, researchers tracked more than 12,000 healthy people over the age of 45 from 1990 to 2016.

Over the 26 years, 5,291 people died. Nearly 1,500 were diagnosed with dementia — 80 per cent with Alzheimer’s — while 1,285 had a stroke and 263 developed Parkinson’s.

The results indicated that the likelihood of women aged 45 years or older getting the diseases was 48 per cent, while it was 36 per cent for men.

The gender split is mostly due to the fact that men die earlier than women, Ikram said.

Two per cent of GDP

“Our study does not show some sort of protective effect for men,” he said. “Instead it is merely due to fewer men surviving to old age.”

Because they live longer, women have an increased risk of such diseases, and the study found women were twice as likely as men to develop both dementia and stroke.

While there are no cures for these diseases, a healthy lifestyle — a good diet, not smoking or having diabetes — can protect against stroke and help prevent the onset of dementia, Ikram said. 

There are also indications that a healthy lifestyle can reduce the risk of Parkinson’s, he added.

The cost of the three neurological diseases is believed to be more than two per cent of the world’s annual economic productivity (GDP), the researchers said in a statement.

However, while the dangers of other illnesses such as breast cancer and heart diseases are well known, “the same can’t be said of dementia, stroke and Parkinsonism”, the statement said.

The researchers noted that as the study only included people of European ancestry with a relatively long life expectancy, it “might not be applicable to other ethnicities/populations”.

Worldwide, about 7 per cent of people over 65 suffer from Alzheimer’s or some form of dementia, a percentage that rises to 40 per cent above the age of 85.

The number afflicted is expected to triple by 2050 to 152 million, according to the World Health Organisation, posing a huge challenge to healthcare systems.